Downstream processing is a supply chain process that is the end process after upstream and midstream
process. The upstream process deals with the fermentation, elimination of waste and the product is
recovered and harvested. The fermenter is determined so that the byproducts and the fermented product
are separated from the broth.
The processing operations begin with the upstream processing and this mostly includes all the initial
operations such as:
Filtration that involves separation operations
Filtration of thermal processing membrane and
Eventually, the purification operations also include the midstream processing, a part of the downstream
processing marketing operations such as packing, drying and storage.
Downstream processing plays a crucial role in pharmaceutical manufacturing companies. This is
because here also it deals with the recovery and purifying of biosynthetic products, thereby includes the
recycling of components, waste disposal and treatment.
Downstream processing is a process that helps in manufacturing or production as it purifies products and
makes it suitable for a particular use in marketable quantity. On the other hand the analytical
bioseparation also is a part of this processing that refers to the purification purpose to measure the mixture
of a component or a component and may also deal with sample sizes.
The influential programs of downstream processing include conditions yielding higher production and
steps to arrive at desired designs and configurations. With the completion of the purification process,
steps are taken to carry out the contaminants resembling the chemical and physical properties of the
product and in this stage downstream processing works to carry out this sophisticated and sensitive
equipment out, thereby adding a fraction to the processing cost.
Finally, before the product is packed, polishing is done, depending on the products need or use and some
undergo sterilizing to eliminate contaminants, thus ensure safety.